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Stereoselective bidirectional synthesis of spiroacetals via Rh(II)-catalysed double C–H insertion
Lepage, Romain J.; Coster, Mark J.
Tetrahedron accepted 24 January 2018

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Synthesis of spirocyclic orthoesters by ‘anomalous’ rhodium(II)-catalysed intramolecular C–H insertions
Lombard, Fanny J.; Lepage, Romain J.; Schwartz, Brett D.; Johnston, Ryne C.; Healy, Peter C.; Krenske, Elizabeth H.; Coster, Mark J.
Org. Biomol. Chem. 2018, 16, 256-261

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Trehalose-6-phosphate phosphatase as a broad-spectrum therapeutic target against eukaryotic and prokaryotic pathogens
Cross, Megan; Rajan, Siji; Biberacher, Sonja; Park, Suk-Youl; Coster, Mark J.; Długosz, Ewa; Kim, Jeong-Sun; Gasser, Robin B.; Hofmann, Andreas
Em. Topics Life Sci. 2017, 1, 675-683

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The design, synthesis, and anti-inflammatory evaluation of a drug-like library based on the natural product valerenic acid.
Egbewande, Folake A.; Nilsson, Niclas; White, Jonathan M.; Coster, Mark J.; Davis, Rohan A.
Bioorg. Med. Chem. Lett. 2017, 27, 3185-3189

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Enzyme characteristics of pathogen-specific trehalose-6-phosphate phosphatases
Cross, Megan; Rajan, Siji; Chekaiban, Janine; Saunders, Jake; Hamilton, Chloe; Coster, Mark J.; Hofmann, Andreas; Kim, Jeong-Sun; Gasser, Robin B.; Hofmann, Andreas; Hofmann, Andreas
Scientific Reports 2017, 7, 2015

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Dichloro-naphthoquinone as a non-classical inhibitor of the mycobacterial carbonic anhydrase Rv3588c.
Dallaston, Madeleine A.; Rajan, Siji; Chekaiban, J.; Wibowo, Mario; Cross, Megan; Coster, Mark J.; Davis, Rohan A.; Hofmann, Andreas
MedChemComm 2017, 8, 1318-1321

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A bidirectional synthesis of spiroacetals via Rh(II)-catalysed C-H insertion.
Lepage, Romain J.; White, Jonathan M.; Coster, Mark J.
Chem. Commun. 2017, 53, 4219-4221

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Probing function and structure of trehalose-6-phosphate phosphatases from pathogenic organisms suggests distinct molecular groupings.
Cross, Megan; Lepage, Romain; Rajan, Siji; Biberacher, Sonja; Young, Neil D.; Kim, Bo-Na; Coster, Mark J.; Gasser, Robin B.; Kim, Jeong-Sun; Hofmann, Andreas
FASEB J. 2017, 31, 920-926, S1-S12

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Synthesis and antiplasmodial evaluation of analogues based on the tricyclic core of Thiaplakortones A-D.
Schwartz, Brett D.; Coster, Mark J.; Skinner-Adams, Tina S.; Andrews, Katherine T.; White, Jonathan M.; Davis, Rohan A.
Mar. Drugs 2015, 13, 5784-5795

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Panel docking of small-molecule libraries - Prospects to improve efficiency of lead compound discovery.
Sarnpitak, Pakornwit; Mujumdar, Prashant; Taylor, Paul; Cross, Megan; Coster, Mark J.; Gorse, Alain-Dominique; Krasavin, Mikhail; Hofmann, Andreas
Biotechnol. Adv. 2015, 33, 941-947

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Rhodium(II)-catalyzed intramolecular C-H insertion α- to oxygen: reactivity, selectivity and applications to natural product synthesis.
Lombard, Fanny J.; Coster, Mark J.
Org. Biomol. Chem. 2015, 13, 6419-6431

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Synthesis of N-alkylsulfonamides by borane-dimethyl sulfide reduction of N-acylsulfonamides.
James, Samantha N.; Coster, Mark J.
Tetrahedron Lett. 2015, 56, 2059-2061

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Synthesis and antimalarial evaluation of amide and urea derivatives based on the thiaplakortone A natural product scaffold.
Schwartz, Brett D.; Skinner-Adams, Tina S.; Andrews, Katherine T.; Coster, Mark J.; Edstein, Michael D.; MacKenzie, Donna; Charman, Susan A.; Koltun, Maria; Blundell, Scott; Campbell, Anna; Pouwer, Rebecca H.; Quinn, Ronald J.; Beattie, Karren D.; Healy, Peter C.; Davis, Rohan A.
Org. Biomol. Chem. 2015, 13, 1558-1570

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Total synthesis of (±)-nicolaioidesin B via a highly regio- and diastereoselective Diels-Alder reaction.
Pigott, Adam J.; Lepage, Romain J.; White, Jonathan M.; Coster, Mark J.
Tetrahedron Lett. 2014, 55, 6864-6867

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Total Synthesis of Thiaplakortone A: Derivatives as Metabolically Stable Leads for the Treatment of Malaria.
Pouwer, Rebecca H.; Deydier, Sophie M.; Van Le, Phuc; Schwartz, Brett D.; Franken, Nicole C.; Davis, Rohan A.; Coster, Mark J.; Charman, Susan A.; Edstein, Michael D.; Skinner-Adams, Tina S.; Andrews, Katherine T.; Jenkins, Ian D.; Quinn, Ronald J.
ACS Med. Chem. Lett. 2014, 5, 178-182

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Synthesis and Evaluation of Anticancer Natural Product Analogues Based on Angelmarin: Targeting the Tolerance towards Nutrient Deprivation.
Magolan, Jakob; Adams, Nathan B. P.; Onozuka, Hiroko; Hungerford, Natasha L.; Esumi, Hiroyasu; Coster, Mark J.
ChemMedChem 2012, 7, 766-770

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Diketoacid Inhibitors of HIV-1 Integrase: From L-708,906 to Raltegravir and Beyond.
Beare, Kaitlin D.; Coster, Mark J.; Rutledge, Peter J.
Curr. Med. Chem 2012, 19, 1177-1192

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3,4’-Linked bis(piperidines) related to the haliclonacyclamine class of marine alkaloids: synthesis using crossed-aldol chemistry and preliminary biological evaluations.
Banwell, Martin G.; Coster, Mark J.; Hungerford, Natasha L.; Garson, Mary J.; Su, Stephen; Kotze, Andrew C.; Munro, Murray H. G.
Org. Biomol. Chem. 2012, 10, 154-161

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Mitochondrially Targeted α-Tocopheryl Succinate Is Antiangiogenic: Potential Benefit Against Tumor Angiogenesis but Caution Against Wound Healing.
Rohlena, Jakub; Dong, Lan-Feng; Kluckova, Katarina; Zobalova, Renata; Goodwin, Jacob; Tilly, David; Stursa, Jan; Pecinova, Alena; Philimonenko, Anatoly; Hozak, Pavel; Banerjee, Jaideep; Ledvina, Miroslav; Sen, Chandan K.; Houstek, Josef; Coster, Mark J.; Neuzil, Jiri.
Antioxid. Redox Signal. 2011, 15, 2923-2935

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First enantioselective synthesis of methyl (+)-7-methoxyanodendroate, an antitubercular dihydrobenzofuran.
Aumann, Kylee M.; Hungerford, Natasha L.; Coster, Mark J.
Tetrahedron Lett. 2011, 52, 6988-6990

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A Concise Route to Dihydrobenzo[b]furans: Formal Total Synthesis of (+)-Lithospermic Acid.
Fischer, Joshua; Savage, G. Paul; Coster, Mark J.
Org. Lett. 2011, 13, 3376-3379

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Arylation of [6,6]-spiroacetal enol ethers: reactivity and rearrangement.
Aumann, Kylee M.; Healy, Peter C.; Coster, Mark J.
Tetrahedron Lett. 2011, 52, 1070-1073

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Mitochondrial Targeting of Vitamin E Succinate Enhances Its Pro-apoptotic and Anti-cancer Activity via Mitochondrial Complex II.
Dong, Lan-Feng; Jameson, Victoria J. A.; Tilly, David; Cerny, Jiri; Mahdavian, Elahe; Marin-Hernandez, Alvaro; Hernandez-Esquivel, Luz; Rodriguez-Enriquez, Sara; Stursa, Jan; Witting, Paul K.; Stantic, Bela; Rohlena, Jakub; Truksa, Jaroslav; Kluckova, Katarina; Dyason, Jeffrey C.; Ledvina, Miroslav; Salvatore, Brian A.; Moreno-Sanchez, Rafael; Coster, Mark J.; Ralph, Stephen J.; Smith, Robin A. J.; Neuzil, Jiri.
J. Biol. Chem. 2011, 286, 3717-3728

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Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: A new paradigm for effective cancer therapy.
Dong, Lan-Feng; Jameson, Victoria J. A.; Tilly, David; Prochazka, Lubomir; Rohlena, Jakub; Valis, Karel; Truksa, Jaroslav; Zobalova, Renata; Mahdavian, Elahe; Kluckova, Katarina; Stantic, Marina; Stursa, Jan; Freeman, Ruth; Witting, Paul K.; Norberg, Erik; Goodwin, Jacob; Salvatore, Brian A.; Novotna, Jana; Turanek, Jaroslav; Ledvina, Miroslav; Hozak, Pavel; Zhivotovsky, Boris; Coster, Mark J.; Ralph, Stephen J.; Smith, Robin A. J.; Neuzil, Jiri.
Free Radic. Biol. Med. 2011, 50, 1546-1555

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Targeting the resistance of pancreatic cancer cells to nutrient deprivation: anti-austerity compounds.
Magolan, Jakob; Coster, Mark J.
Curr. Drug Deliv. 2010, 7, 355-369

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Oxo-bridged isomers of aza-trishomocubane sigma (σ) receptor ligands: Synthesis, in vitro binding, and molecular modeling.
Banister, Samuel D.; Moussa, Iman A.; Jordan, Meredith J. T.; Coster, Mark J.; Kassiou, Michael.
Bioorg. Med. Chem. Lett. 2010, 20, 145-148

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Purinergic P2X7 receptor antagonists: Chemistry and fundamentals of biological screening.
Gunosewoyo, Hendra; Coster, Mark J.; Bennett, Maxwell R.; Kassiou, Michael.
Bioorg. Med. Chem. 2009, 17, 4861-4865

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Total Synthesis of (+)-Angelmarin.
Magolan, Jakob; Coster, Mark J.
J. Org. Chem. 2009, 74, 5083-5086

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Synthesis and In-Vivo Evaluation of [11C]p-PVP-MEMA as a PET Radioligand for Imaging Nicotinic Receptors.
Dolle, Frederic; Langle, Sandrine; Roger, Gaelle; Fulton, Roger R.; Lagnel-de Bruin, Beatrice; Henderson, David J.; Hinnen, Francoise; Paine, Taliesha; Coster, Mark J.; Valette, Heric; Bottlaender, Michel; Kassiou, Michael.
Aust. J. Chem. 2008, 61, 438-445

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Cubyl amides: Novel P2X7 receptor antagonists.
Gunosewoyo, Hendra; Guo, Jun Liu; Bennett, Maxwell R.; Coster, Mark J.; Kassiou, Michael.
Bioorg. Med. Chem. Lett. 2008, 18, 3720-3723

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Trishomocubanes: Novel σ ligands modulate cocaine-induced behavioral effects.
Liu, Xiang; Banister, Samuel D.; Christie, MacDonald J.; Banati, Richard; Meikle, Steve; Coster, Mark J.; Kassiou, Michael.
Eur. J. Pharmacol. 2007, 555, 37-42

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Reversibility in the boron-mediated ketone-ketone aldol reaction.
Cergol, Katie M.; Jensen, Paul; Turner, Peter; Coster, Mark J.
Chem. Commun. 2007, 1363-1365

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Molecular probes for P2X7 receptor studies.
Gunosewoyo, Hendra; Coster, Mark J.; Kassiou, Michael.
Curr. Med. Chem. 2007, 14, 1505-1523

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Asymmetric aldol reaction using boron enolates.
Cergol, Katie M.; Coster, Mark J.
Nat. Protoc. 2007, 2, 2568-2573

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(1R,2S,3R,6S,7R,8S)-tricyclo[6.2.1.02,7]undeca-4,9-diene-3,6-diol.
Banister, Samuel D.; Clegg, Jack K.; Coster, Mark J.; Jolliffe, Katrina A.; Kassiou, Michael.
Acta Crystallographica, Section E: Structure Reports Online 2007, 63, o92-o93

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Regioselective Reduction of 3-Methoxymaleimides: An Efficient Method for the Synthesis of Methyl 5-Hydroxytetramates.
Issa, Fatiah; Fischer, Joshua; Turner, Peter; Coster, Mark J.
J. Org. Chem. 2006, 71, 4703-4705

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The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: the southern hemisphere EF segment.
Paterson, Ian; Coster, Mark J.; Chen, David Y.-K.; Acena, Jose L.; Bach, Jordi; Keown, Linda E.; Trieselmann, Thomas.
Org. Biomol. Chem. 2005, 3, 2420-2430

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The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: the CD-spiroacetal segment.
Paterson, Ian; Coster, Mark J.; Chen, David Y.-K.; Gibson, Karl R.; Wallace, Debra J.
Org. Biomol. Chem. 2005, 3, 2410-2419

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The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: the AB-spiroacetal segment.
Paterson, Ian; Coster, Mark J.; Chen, David Y.-K.; Oballa, Renata M.; Wallace, Debra J.; Norcross, Roger D.
Org. Biomol. Chem. 2005, 3, 2399-2409

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The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: fragment couplings, completion of the synthesis, analogue generation and biological evaluation.
Paterson, Ian; Chen, David Y.-K.; Coster, Mark J.; Acena, Jose L.; Bach, Jordi; Wallace, Debra J.
Org. Biomol. Chem. 2005, 3, 2431-2440

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The boron-mediated ketone-ketone aldol reaction.
Cergol, Katie M.; Turner, Peter; Coster, Mark J.
Tetrahedron Lett. 2005, 46, 1505-1509

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Total Synthesis of Spongistatin 1 (Altohyrtin A): A Tale of Ten Aldols.
Paterson, Ian; Coster, Mark J.
Strategies and Tactics in Organic Synthesis Editor: Michael Harmata. 2005, Vol. 4, 211-245. Elsevier: Oxford.

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CP-225,917 and CP-263,114 synthesis support studies: Testing a radical cyclization strategy for installation of the side-chains.
Banwell, Martin G.; Coster, Mark J.; Edwards, Alison J.; Voegtle, Markus.
Aust. J. Chem. 2003, 56, 577-583

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A total synthesis of the styryllactone (+)-goniodiol from naphthalene.
Banwell, Martin G.; Coster, Mark J.; Edwards, Alison J.; Karunaratne, Ochitha P.; Smith, Jason A.; Welling, Lee L.; Willis, Anthony C.
Aust. J. Chem. 2003, 56, 585-595

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Synthesis and biological evaluation of spongistatin/altohyrtin analogues: E-ring dehydration and C46 side-chain truncation.
Paterson, Ian; Acena, Jose L.; Bach, Jordi; Chen, David Y.-K.; Coster, Mark J.
Chem. Commun. 2003, 462-463

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Selective Cleavage of N-Benzyl-Protected Secondary Amines by Triphosgene.
Banwell, Martin G.; Coster, Mark J.; Harvey, Michael J.; Moraes, John.
J. Org. Chem. 2003, 68, 613-616

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Total synthesis of altohyrtin A (spongistatin 1): an alternative synthesis of the CD-spiroacetal subunit.
Paterson, Ian; Coster, Mark J.
Tetrahedron Lett. 2002, 43, 3285-3289

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Medium Ring Ethers by Ring Expansion-Ring Contraction: Synthesis of Lauthisan.
Coster, Mark J.; De Voss, James J.
Org. Lett. 2002, 4, 3047-3050

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A chemoenzymatic synthesis of the styryllactone (+)-goniodiol from naphthalene.
Banwell, Martin G.; Coster, Mark J.; Karunaratne, Ochitha P.; Smith, Jason A.
J. Chem. Soc., Perkin Trans. 1 2002, 1622-1624

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Stereocontrolled total synthesis of (+)-altohyrtin A/spongistatin 1.
Paterson, Ian; Chen, David Y.-K.; Coster, Mark J.; Acena, Jose L.; Bach, Jordi; Gibson, Karl R.; Keown, Linda E.; Oballa, Renata M.; Trieselmann, Thomas; Wallace, Debra J.; Hodgson, Andrew P.; Norcross, Roger D.
Angew. Chem. Int. Ed. 2001, 40, 4055-4060

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